Home Tools

Casein Kinase

The Casein kinase 1 family of protein kinases are serine/threonine-selective enzymes that function as regulators of signal transduction pathways in most eukaryotic cell types. CK1 isoforms are involved in Wnt signaling, circadian rhythms, nucleo-cytoplasmic shuttling of transcription factors, DNA repair, and DNA transcription.

Cat. No.	Product name	CAS No.	Purity
T4645	TA-01	1784751-18-3	98%
T4645	TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.
T2449	D4476	301836-43-1	98%
T2449	D4476 is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).
T2048	LY-364947	396129-53-6	98%
T2048	LY364947 is a potent ATP-competitive inhibitor of TGFβR-I.

TA-01

T4645

TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.

D4476

T2449

D4476 is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).

LY-364947

T2048

LY364947 is a potent ATP-competitive inhibitor of TGFβR-I.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.