Home Tools
Log in
Cart

CCR

CC chemokine receptors (or beta chemokine receptors) are integral membrane proteins that specifically bind and respond to cytokines of the CC chemokine family. They represent one subfamily of chemokine receptors, a large family of G protein-linked receptors that are known as seven transmembrane (7-TM) proteins since they span the cell membrane seven times. To date, ten true members of the CC chemokine receptor subfamily have been described. These are named CCR1 to CCR10 according to the IUIS/WHO Subcommittee on Chemokine Nomenclature.
Cat. No. Product name CAS No. Purity Chemical Structure
T23321 SB 328437 247580-43-4 99.11%
SB 328437 is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).
T17225 Vercirnon 698394-73-9 99.15%
Vercirnon is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.
TQ0283 RS102895 300815-41-2 99.54%
RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.
T6016 Maraviroc 376348-65-1 99.55%
Maraviroc is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1α(IC50=3.3 nM), MIP-1β (IC50=7.2 nM) and RANTES(IC50=5.2 nM).Maraviroc inhibits HIV-...
T7499 TAK-779 229005-80-5 99.58%
TAK-779 is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).
TN1273 7,4'-Dihydroxyflavone 2196-14-7 99.6%
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
T14900 CCR2-RA-[R] 512177-83-2 99.65%
CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).
T4674 SB297006 58816-69-6 99.65%
SB 297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ....
T12773 RS102895 hydrochloride 1173022-16-6 99.7%
RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).
T21870 C-021 864289-85-0 99.74%
C 021 dihydrochloride is a potent CCR4 antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in humans and mice with IC50s of 140 nM and 39 n...
T3327 Artemotil 75887-54-6 99.76%
Arteether is a new, fast-acting antimalarial drug.
T4584 BMS-813160 1286279-29-5 99.78%
BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.
T11481 GSK2239633A 1240516-71-5 99.78%
GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 for the binding of [125I]-TARC to human CCR4.
T60145 CCR6 antagonist 1 588674-64-0 99.89%
CCR6 antagonist 1 is a CCR6 antagonist. CCR6 antagonist 1 inhibits the CCL20/CCR6 axis. CCR6 antagonist 1 can be used in the research of autoimmune-mediated infl...
T3430 PF-4136309 1341224-83-6 99.9%
INCB8761(PF-4136309) is a specific, effective, and orally bioavailable CCR2 antagonist.
T3188 NSC5844 140926-75-6 99.91%
NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.
T16111 ML604086 850330-18-6 99.91%
ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations. ML604086 is a selective inhibitor of CCR8. It also inhibiting CCL1 bi...
T4300 AZD2098 566203-88-1 99.92%
AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.
T2375 BX471 217645-70-0 99.94%
BX471 is a potent, selective non-peptide CCR1 antagonist.
T14909 CCX140 1100318-47-5 99.95%
CCX140 (CCX140-B) is an antagonist of CCR2.
SB 328437
T23321
SB 328437 is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).
Vercirnon
T17225
Vercirnon is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.
RS102895
TQ0283
RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.
Maraviroc
T6016
Maraviroc is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1α(IC50=3.3 nM), MIP-1β (IC50=7.2 nM) and RANTES(IC50=5.2 nM).Maraviroc inhibits HIV-...
TAK-779
T7499
TAK-779 is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).
7,4'-Dihydroxyflavone
TN1273
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
CCR2-RA-[R]
T14900
CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).
SB297006
T4674
SB 297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ....
RS102895 hydrochloride
T12773
RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).
C-021
T21870
C 021 dihydrochloride is a potent CCR4 antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in humans and mice with IC50s of 140 nM and 39 n...
Artemotil
T3327
Arteether is a new, fast-acting antimalarial drug.
BMS-813160
T4584
BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.
GSK2239633A
T11481
GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 for the binding of [125I]-TARC to human CCR4.
CCR6 antagonist 1
T60145
CCR6 antagonist 1 is a CCR6 antagonist. CCR6 antagonist 1 inhibits the CCL20/CCR6 axis. CCR6 antagonist 1 can be used in the research of autoimmune-mediated infl...
PF-4136309
T3430
INCB8761(PF-4136309) is a specific, effective, and orally bioavailable CCR2 antagonist.
NSC5844
T3188
NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.
ML604086
T16111
ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations. ML604086 is a selective inhibitor of CCR8. It also inhibiting CCL1 bi...
AZD2098
T4300
AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.
BX471
T2375
BX471 is a potent, selective non-peptide CCR1 antagonist.
CCX140
T14909
CCX140 (CCX140-B) is an antagonist of CCR2.
1 2 3 4