T23321 |
SB 328437
|
247580-43-4
|
99.11%
|
|
SB 328437 is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).
|
T17225 |
Vercirnon
|
698394-73-9
|
99.15%
|
|
Vercirnon is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.
|
TQ0283 |
RS102895
|
300815-41-2
|
99.54%
|
|
RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.
|
T6016 |
Maraviroc
|
376348-65-1
|
99.55%
|
|
Maraviroc is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1α(IC50=3.3 nM), MIP-1β (IC50=7.2 nM) and RANTES(IC50=5.2 nM).Maraviroc inhibits HIV-...
|
T7499 |
TAK-779
|
229005-80-5
|
99.58%
|
|
TAK-779 is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).
|
TN1273 |
7,4'-Dihydroxyflavone
|
2196-14-7
|
99.6%
|
|
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
|
T14900 |
CCR2-RA-[R]
|
512177-83-2
|
99.65%
|
|
CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).
|
T4674 |
SB297006
|
58816-69-6
|
99.65%
|
|
SB 297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ....
|
T12773 |
RS102895 hydrochloride
|
1173022-16-6
|
99.7%
|
|
RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).
|
T21870 |
C-021
|
864289-85-0
|
99.74%
|
|
C 021 dihydrochloride is a potent CCR4 antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in humans and mice with IC50s of 140 nM and 39 n...
|
T3327 |
Artemotil
|
75887-54-6
|
99.76%
|
|
Arteether is a new, fast-acting antimalarial drug.
|
T4584 |
BMS-813160
|
1286279-29-5
|
99.78%
|
|
BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.
|
T11481 |
GSK2239633A
|
1240516-71-5
|
99.78%
|
|
GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 for the binding of [125I]-TARC to human CCR4.
|
T60145 |
CCR6 antagonist 1
|
588674-64-0
|
99.89%
|
|
CCR6 antagonist 1 is a CCR6 antagonist. CCR6 antagonist 1 inhibits the CCL20/CCR6 axis. CCR6 antagonist 1 can be used in the research of autoimmune-mediated infl...
|
T3430 |
PF-4136309
|
1341224-83-6
|
99.9%
|
|
INCB8761(PF-4136309) is a specific, effective, and orally bioavailable CCR2 antagonist.
|
T3188 |
NSC5844
|
140926-75-6
|
99.91%
|
|
NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.
|
T16111 |
ML604086
|
850330-18-6
|
99.91%
|
|
ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations. ML604086 is a selective inhibitor of CCR8. It also inhibiting CCL1 bi...
|
T4300 |
AZD2098
|
566203-88-1
|
99.92%
|
|
AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.
|
T2375 |
BX471
|
217645-70-0
|
99.94%
|
|
BX471 is a potent, selective non-peptide CCR1 antagonist.
|
T14909 |
CCX140
|
1100318-47-5
|
99.95%
|
|
CCX140 (CCX140-B) is an antagonist of CCR2.
|