Beta Amyloid

Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ. Aβ molecules can aggregate to form flexible soluble oligomers which may exist in several forms. It is now believed that certain misfolded oligomers (known as "seeds") can induce other Aβ molecules to also take the misfolded oligomeric form, leading to a chain reaction akin to a prion infection.

Cat. No.	Product name	CAS No.	Purity
T3914	Saikosaponin C	20736-08-7	98%
Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.
T7003	Leucomethylene blue mesylate	1236208-20-0	98%
TRx 0237 (LMTX) mesylate is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia.
TN1798	Isorosmanol	93780-80-4	98%
Isorosmanol possesses antioxidant, neuroprotective and neurotrophic effects, it might be useful in ageing disorders such as the declining of cognitive functions ...
TN1653	Fustin	20725-03-5	98%
Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.
T19011	Hoechst 34580	23555-00-2	98%
Hoechst 34580, a cell-permeable fluorescent dye, is used for staining DNA and nuclei.
TP2419	V-9-M Cholecystokinin nonapeptide	99291-20-0	98%
V-9-M cholecystokinin non-peptide is a precursor compound of cholecystokinin (CCK). Cholecystokinin (CCK) is a brain-intestinal peptide that stimulates gallbladd...
TP1007	β-Amyloid (1-42), human	107761-42-2	98%
Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.

Cat. No.

Product name

CAS No.

Purity

Chemical Structure

T3914

Saikosaponin C

20736-08-7

98%

Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.

T7003

Leucomethylene blue mesylate

1236208-20-0

98%

TRx 0237 (LMTX) mesylate is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia.

TN1798

Isorosmanol

93780-80-4

98%

Isorosmanol possesses antioxidant, neuroprotective and neurotrophic effects, it might be useful in ageing disorders such as the declining of cognitive functions ...

TN1653

Fustin

20725-03-5

98%

Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.

T19011

Hoechst 34580

23555-00-2

98%

Hoechst 34580, a cell-permeable fluorescent dye, is used for staining DNA and nuclei.

TP2419

V-9-M Cholecystokinin nonapeptide

99291-20-0

98%

V-9-M cholecystokinin non-peptide is a precursor compound of cholecystokinin (CCK). Cholecystokinin (CCK) is a brain-intestinal peptide that stimulates gallbladd...

TP1007

β-Amyloid (1-42), human

107761-42-2

98%

Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.