Beta Amyloid

Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ. Aβ molecules can aggregate to form flexible soluble oligomers which may exist in several forms. It is now believed that certain misfolded oligomers (known as "seeds") can induce other Aβ molecules to also take the misfolded oligomeric form, leading to a chain reaction akin to a prion infection.

Cat. No.	Product name	CAS No.	Purity	Chemical Structure
TP1856	Colivelin	867021-83-8	96.56%
TP1856	Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).
TN1027	β-Amyrin	559-70-6	96.49%
TN1027	β-Amyrin (beta-Amyrin) has antiviral, hepatoprotective, antinociceptive, anti-inflammatory
TP1359L	Amyloid β Peptide (42-1)(human) acetate		95.20%
TP1359L	Amyloid β Peptide (42-1)(human) acetate is the inactive form of Amyloid β Peptide (1-42). Amyloid β Peptide (42-1)(human) acetate is a 42-amino acid peptide whic...
T28441	PPI-1019	290828-45-4	95.16%
T28441	PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).
T0795	Rutin	153-18-4	95%
T0795	Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarci...
T14673	BMS 299897	290315-45-6	100%
T14673	BMS 299897 is a sulfonamide γ-secretase inhibitor. It has an IC50 of 7 nM for Aβ production inhibition in HEK293 cells stably overexpressing amyloid precursor pr...
TP1866L	β-amyloid 1-11 acetate(190436-05-6 free base)	TP1866L	100%
TP1866L	β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.
T22204	LY 2389575 hydrochloride	885104-09-6	100%
T22204	LY2389575 hydrochloride is an mGlu3 negative allosteric modulator (NAM) that is selective and non-competitive, with an IC50 value of 190 nM. LY2389575 hydrochlor...
T7562	β-Amyloid (31-35)	149385-65-9	100%
T7562	β-Amyloid (31-35) (β-Amyloid 31-35) is the shortest sequence of native Amyloid-β peptide.
T7905	PBD-150	790663-33-1	100%
T7905	PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)
TQ0026	MDR-1339	1018946-38-7
TQ0026	MDR-1339 (DWK-1339) is an orally active and blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.
T2873	Ginsenoside Rg2	52286-74-5
T2873	Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor.
T22932L	LPYFD-NH2 acetate
T22932L	LPYFD-NH2 acetate shows some inhibitory effect on the aggregation of Abeta(1-42).
TN1341	8-Deoxygartanin	33390-41-9
TN1341	8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has mu...
TP1935L1	RAGE antagonist peptide acetate	TP1935L1	98%
TP1935L1	RAGE antagonist peptide acetate is an advanced antagonist of glycation end products (RAGE). RAGE antagonist peptide acetate possesses anti-tumor and anti-inflamm...
T77042	Aducanumab	1384260-65-4	98%	Aducanumab
T77042	Aducanumab (BIIB037), A selective human immunoglobulin gamma-1 (IgG1) monoclonal antibody, targets the clustered form of amyloid beta (Aβ). Aducanumab shows brai...			Aducanumab
T77054	Lecanemab	1260393-98-3	98%	Lecanemab
T77054	Lecanemab (BAN-2401), an IgG1 monoclonal antibody targeting soluble aggregated amyloid beta (Aβ), demonstrates efficacy across Aβ oligomers, protofibrils, and in...			Lecanemab
T7680	GSNKGAIIGLM(131602-53-4(free base))	T7680	98%
T7680	GSNKGAIIGLM(131602-53-4(free base)) (Amyloid beta-peptide(25-35)) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide.
T38469	(Rac)-Z-Phe-Phe-FMK	108005-94-3	98%
T38469	(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .