TN4635 |
Neoechinulin A
|
51551-29-2
|
98%
|
|
Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the ...
|
TN3218 |
7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one
|
100667-52-5
|
98%
|
|
7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one as a beneficial compound to ameliorate the deleterious effects of Aβ on dendrite integrity and cell survival, and may...
|
T19142 |
4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine
|
566169-98-0
|
98%
|
|
4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).
|
T10453 |
BACE1-IN-5
|
T10453
|
98%
|
|
BACE1-IN-5 (Compound 15) is a β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC 50 of 9.1 nM. BACE1-IN-5 also inhibits cellular amy...
|
T19013 |
Hoechst 34580 tetrahydrochloride
|
T19013
|
98%
|
|
Hoechst 34580 tetrahydrochloride, a cell-permeable fluorescent dye, is used for staining DNA and nuclei.
|
TN4571 |
Mirabijalone D
|
485811-84-5
|
98%
|
|
Mirabijalone D is a non-competitive inhibitor based on the Dixon plot.It inhibits Aβ1-42 production by 43.7% in APPSW-N2a cells.
|
T6562 |
Latrepirdine dihydrochloride
|
97657-92-6
|
98%
|
|
Latrepirdine is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihi...
|
TN3618 |
Cedrin
|
75513-81-4
|
98%
|
|
Cedrin has protective effects on PC12 cells against the neurotoxicity induced by amyloid β1-42, the protective effect is related to the inhibition of oxidative s...
|
TN4865 |
Putraflavone
|
23624-21-7
|
98%
|
|
Putraflavone possesses a good antioxidant activity via its DPPH free radical scavenging.
|
TN1919 |
(+)-Medioresinol
|
40957-99-1
|
98%
|
|
Medioresinol possesses antioxidative, a lesishmanicidal activity and cardiovascular disease risk reduction, it has antiamyloidogenic activity via reduction in th...
|
TN3410 |
Anatabine
|
581-49-7
|
98%
|
|
Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via an inhibition of STAT3 phosphorylation.Anatabine has anti-Alzheime...
|
T14673 |
BMS 299897
|
290315-45-6
|
98%
|
|
BMS 299897 is a sulfonamide γ-secretase inhibitor. It has an IC50 of 7 nM for Aβ production inhibition in HEK293 cells stably overexpressing amyloid precursor pr...
|
T14525 |
Begacestat
|
769169-27-9
|
98%
|
|
Begacestat is a selective thiophene sulfonamide amyloid precursor protein gamma-secretase inhibitor (Aβ40,IC50=15 nM),and for the treatment of Alzheimer's diseas...
|
T7566L1 |
GRGDSPK acetate
|
144027-77-0
|
98%
|
|
GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.
|
T22932L |
LPYFD-NH2 acetate
|
|
98%
|
|
LPYFD-NH2 acetate shows some inhibitory effect on the aggregation of Abeta(1-42).
|
TQ0026 |
MDR-1339
|
1018946-38-7
|
98%
|
|
MDR-1339 (DWK-1339) is an orally active and blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.
|
TP1935L1 |
RAGE antagonist peptide acetate
|
TP1935L1
|
98%
|
|
RAGE antagonist peptide acetate is an advanced antagonist of glycation end products (RAGE). RAGE antagonist peptide acetate possesses anti-tumor and anti-inflamm...
|
TN1116 |
Schisandrone
|
98619-25-1
|
98%
|
|
Schisandrone has strong activities of anti-oxidation, effectively scavenges hydroxyl radical and superoxide anion, and has protective effects on cells under acti...
|
TN2211 |
Silybin B
|
142797-34-0
|
98%
|
|
Silybin B is an effective inhibitor of raloxifene 4 '- and 6-glucosalylation, an effective anti-fibrinogenic and anti-oligomeric component of Silymarin, with fre...
|
T5810 |
TABERSONINE HYDROCHLORIDE
|
29479-00-3
|
98%
|
|
TABERSONINE HYDROCHLORIDE is a natural product extracted from the bean of Voacanga africana, is a potent inhibitor against Aβ(1 42) aggregation and toxicity.
|