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Androgen Receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
Cat. No. Product name CAS No. Purity Chemical Structure
T9752 3-(7,7-dimethyl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)-1H-indole-7-carbonitrile 2759137-87-4 98%
3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.
T24943 VPC-14228 19983-28-9 98%
VPC-14228 is a specific AR-DBD inhibitor that acts by inhibiting both Y594A and Q592A mutants.
T10359 AR antagonist 1 1818885-54-9
AR antagonist 1 is a potent antagonist of the androgen receptor. It binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PR...
T19470 Nandrolone propionate 7207-92-3
Nandrolone propionate is an anabolic steroid action primarily consisting of androgenic and nitrogen-retentive properties.
T2991 3,3'-Diindolylmethane 1968-05-4 100%
DIM (3, 3'-diindolylmethane), a small molecule compound, is a proposed Y preventive agent.
T8117 Metenolone acetate 434-05-9 100%
Methenolone acetate is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure.
T6400 AZD3514 1240299-33-5 96.6%
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
T6889 MI-136 1628316-74-4 97.08%
MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.
T21740 RD162 915087-27-3 97.74%
RD162 is a non-steroidal antiandrogen (NSAA) specifically binding to the androgen receptor (AR).
T7358 YK11 1370003-76-1 98%
YK11 is an androgen receptor partial agonist that activates androgen receptor transcriptional activity in HEK293 cells overexpressing androgen receptors when use...
T7440 P,p'-DDE 72-55-9 98%
4,4'-DDE is a metabolite and degradation product of the organochlorine pesticide DDT
T13273 UT-34 2168525-92-4 98.1%
UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-...
T2207 Adrenosterone 382-45-6 98.13%
Adrenosterone is a steroid hormone isolated from the adrenal cortex.
T1596 Chlormadinone acetate 302-22-7 98.18%
Chlormadinone acetate is an orally active synthetic progestational hormone used often in combinations as an oral contraceptive.
T8933 JNJ-63576253 free base 2110426-27-0 98.32%
JNJ-63576253 is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP ce...
T1167 Cyproterone acetate 427-51-0 98.43%
Cyproterone binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and inhibiting the growth of testosterone...
T9035 Testosterone undecanoate 5949-44-0 98.47%
Testosterone undecanoate is a metabolite of Testosterone, which is a promising androgen for male hormonal contraception.
T7690 2-hydroxy Flutamide 52806-53-8 98.53%
2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer
T20789 S-23 1010396-29-8 98.55%
S-23 is a novel nonsteroidal agonist and has tissue selective.
T12323 ORM-15341 1297537-33-7 98.61%
ORM-15341 is a potent and full antagonist for human AR (hAR)( with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells)
3-(7,7-dimethyl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)-1H-indole-7-carbonitrile
T9752
3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.
VPC-14228
T24943
VPC-14228 is a specific AR-DBD inhibitor that acts by inhibiting both Y594A and Q592A mutants.
AR antagonist 1
T10359
AR antagonist 1 is a potent antagonist of the androgen receptor. It binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PR...
Nandrolone propionate
T19470
Nandrolone propionate is an anabolic steroid action primarily consisting of androgenic and nitrogen-retentive properties.
3,3'-Diindolylmethane
T2991
DIM (3, 3'-diindolylmethane), a small molecule compound, is a proposed Y preventive agent.
Metenolone acetate
T8117
Methenolone acetate is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure.
AZD3514
T6400
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
MI-136
T6889
MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.
RD162
T21740
RD162 is a non-steroidal antiandrogen (NSAA) specifically binding to the androgen receptor (AR).
YK11
T7358
YK11 is an androgen receptor partial agonist that activates androgen receptor transcriptional activity in HEK293 cells overexpressing androgen receptors when use...
p,p'-DDE
T7440
4,4'-DDE is a metabolite and degradation product of the organochlorine pesticide DDT
UT-34
T13273
UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-...
Adrenosterone
T2207
Adrenosterone is a steroid hormone isolated from the adrenal cortex.
Chlormadinone acetate
T1596
Chlormadinone acetate is an orally active synthetic progestational hormone used often in combinations as an oral contraceptive.
JNJ-63576253 free base
T8933
JNJ-63576253 is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP ce...
Cyproterone acetate
T1167
Cyproterone binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and inhibiting the growth of testosterone...
Testosterone undecanoate
T9035
Testosterone undecanoate is a metabolite of Testosterone, which is a promising androgen for male hormonal contraception.
2-hydroxy Flutamide
T7690
2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer
S-23
T20789
S-23 is a novel nonsteroidal agonist and has tissue selective.
ORM-15341
T12323
ORM-15341 is a potent and full antagonist for human AR (hAR)( with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells)
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