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Adrenergic Receptor

The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications like beta blockers, β2 agonists and α2 agonists, which are used to treat high blood pressure and asthma, for example.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T2306 Brexpiprazole 913611-97-9 99.69%
Brexpiprazole
Brexpiprazole (OPC-34712) is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors.
T2546 Pimozide 2062-78-4 99.69%
Pimozide
Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopamine...
T10830 CL 316243 138908-40-4 99.68%
CL 316243
CL316243 is a highly potent selective agonist of β3-adrenoceptor, with a EC50 of 3 nM. CL316243 is an effective stimulant of adipocyte lipolysis and increases br...
T13403 ZK-90055 hydrochloride 84638-81-3 99.67%
ZK-90055 hydrochloride
ZK-90055 hydrochloride is a β2 adrenergic receptor agonist used to study asthma.
T19680 Zotepine 26615-21-4 99.67%
Zotepine
Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3...
T22905 L748337 244192-94-7 99.67%
L748337
L748337 is a competitive and potent β3-adrenoceptor antagonist that inhibits the action of β3-, β2-, and β1-adrenoceptors, activates MAPK signaling, promotes pho...
T21446 Rotigotine Hydrochloride 125572-93-2 99.66%
Rotigotine Hydrochloride
Rotigotine Hydrochloride (N-0924), a dopamine receptor agonist prefering for D3 receptors over D1 and D2, has effective activity of anti-Parkinsonian. Racemic ro...
T10758L Centanafadine hydrochloride 923981-14-0 99.66%
Centanafadine hydrochloride
Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC...
T10168 5-HT1A modulator 1 142477-34-7 99.66%
5-HT1A modulator 1
5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).
T23397 ST 91 4749-61-5 99.64%
ST 91
ST-91 is an agonist of α2-adrenoceptor with a mixed α-adrenergic receptor type/subtype selection profile.
T6963 Reboxetine mesylate 98769-84-7 99.64%
Reboxetine mesylate
Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).
T11894 Lusaperidone 214548-46-6 99.64%
Lusaperidone
Lusaperidone (R107474) is a potent α2-adrenergic receptor antagonist, a potential radioligand for the α (2)-adrenergic receptor, with inhibitory effects on α2A a...
T0783 Mianserin hydrochloride 21535-47-7 99.63%
Mianserin hydrochloride
Mianserin hydrochloride (Org GB 94) is a tetracyclic compound with antidepressant effects. it apparently blocks alpha-adrenergic, histamine H1, and some types of...
T1090 Perphenazine 58-39-9 99.63%
Perphenazine
Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
T22852 ICI 89406 53671-71-9 99.62%
ICI 89406
ICI 89406 (1-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-3-phenylurea) is a β-adrenergic antagonist.
T1632 Amitraz 33089-61-1 99.62%
Amitraz
Amitraz (NSC 324552) is a white monoclinic crystals. Melting point 187-189°F (86-87°C). Insoluble in water. Used as an acaricide, insecticide and treatment of de...
T34308 Rezatomidine 847829-38-3 99.62%
Rezatomidine
Rezatomidine (AGN203818) is a selective antagonist of α2-adrenergic receptor and can be used in studies about chronic pain, including neuropathic pain.
T0091 Alfuzosin hydrochloride 81403-68-1 99.61%
Alfuzosin hydrochloride
Alfuzosin hydrochloride (Alfuzosin HCl) is an α1 adrenergic receptor antagonist. It applies to treat benign prostatic hyperplasia (BPH).
T4526 Piperoxan hydrochloride 135-87-5 99.59%
Piperoxan hydrochloride
Piperoxan hydrochloride (Benodaine hydrochloride) is an α2 adrenoceptor antagonist. Piperoxan (benodaine) is a drug which was the very first antihistamine to be ...
T21957 Guanabenz hydrochloride 23113-43-1 99.59%
Guanabenz hydrochloride
Guanabenz hydrochloride (NE56490) is an orally active α2-adrenoceptor agonist with hypotensive effects.
Brexpiprazole
T2306
Brexpiprazole (OPC-34712) is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors.
Pimozide
T2546
Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopamine...
CL 316243
T10830
CL316243 is a highly potent selective agonist of β3-adrenoceptor, with a EC50 of 3 nM. CL316243 is an effective stimulant of adipocyte lipolysis and increases br...
ZK-90055 hydrochloride
T13403
ZK-90055 hydrochloride is a β2 adrenergic receptor agonist used to study asthma.
Zotepine
T19680
Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3...
L748337
T22905
L748337 is a competitive and potent β3-adrenoceptor antagonist that inhibits the action of β3-, β2-, and β1-adrenoceptors, activates MAPK signaling, promotes pho...
Rotigotine Hydrochloride
T21446
Rotigotine Hydrochloride (N-0924), a dopamine receptor agonist prefering for D3 receptors over D1 and D2, has effective activity of anti-Parkinsonian. Racemic ro...
Centanafadine hydrochloride
T10758L
Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC...
5-HT1A modulator 1
T10168
5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).
ST 91
T23397
ST-91 is an agonist of α2-adrenoceptor with a mixed α-adrenergic receptor type/subtype selection profile.
Reboxetine mesylate
T6963
Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).
Lusaperidone
T11894
Lusaperidone (R107474) is a potent α2-adrenergic receptor antagonist, a potential radioligand for the α (2)-adrenergic receptor, with inhibitory effects on α2A a...
Mianserin hydrochloride
T0783
Mianserin hydrochloride (Org GB 94) is a tetracyclic compound with antidepressant effects. it apparently blocks alpha-adrenergic, histamine H1, and some types of...
Perphenazine
T1090
Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
ICI 89406
T22852
ICI 89406 (1-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-3-phenylurea) is a β-adrenergic antagonist.
Amitraz
T1632
Amitraz (NSC 324552) is a white monoclinic crystals. Melting point 187-189°F (86-87°C). Insoluble in water. Used as an acaricide, insecticide and treatment of de...
Rezatomidine
T34308
Rezatomidine (AGN203818) is a selective antagonist of α2-adrenergic receptor and can be used in studies about chronic pain, including neuropathic pain.
Alfuzosin hydrochloride
T0091
Alfuzosin hydrochloride (Alfuzosin HCl) is an α1 adrenergic receptor antagonist. It applies to treat benign prostatic hyperplasia (BPH).
Piperoxan hydrochloride
T4526
Piperoxan hydrochloride (Benodaine hydrochloride) is an α2 adrenoceptor antagonist. Piperoxan (benodaine) is a drug which was the very first antihistamine to be ...
Guanabenz hydrochloride
T21957
Guanabenz hydrochloride (NE56490) is an orally active α2-adrenoceptor agonist with hypotensive effects.
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TargetMol