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AChR

An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T8219 VU0238441 85511-68-8 100%
VU0238441
VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.
T2663 GTS-21 dihydrochloride 156223-05-1 100%
GTS-21 dihydrochloride
GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh.
T12481 Pipecuronium bromide 52212-02-9 100%
Pipecuronium bromide
Pipecuronium bromide (RGH-1106) is a selective and potent nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker, causing muscle r...
T28257L (-)-OPC-51803 192514-57-1 100%
(-)-OPC-51803
(-)-OPC-51803 is an antidiuretic hormone V2 receptor agonist used in the treatment of nocturia and urinary incontinence.
T6364 Desfesoterodine 207679-81-0 100%
Desfesoterodine
Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.
T0018 Procainamide hydrochloride 614-39-1 100%
Procainamide hydrochloride
Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog ...
T19870 Aceclidine 827-61-2 100%
Aceclidine
Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocular pressure...
T8007 VU 0238429 1160247-92-6 100%
VU 0238429
VU 0238429 (SCR-1481B1) is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).
T2390 Cevimeline hydrochloride hemihydrate 153504-70-2 100%
Cevimeline hydrochloride hemihydrate
Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.
T0172 Maprotiline hydrochloride 10347-81-6 100%
Maprotiline hydrochloride
Maprotiline hydrochloride (Psymion) is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepre...
T13992 CHF5407 1004312-94-0 100%
CHF5407
CHF5407(SVT-47060) is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect on bronchospas...
T1336 Benztropine mesylate 132-17-2 100%
Benztropine mesylate
Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISE...
T8318 BNC210 13589-06-5 100%
BNC210
BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
T2759 Loganin 18524-94-2 100%
Loganin
Loganin (Loganoside), an iridoid glucoside, has been reported to be an inhibitor of Cox-1 and also noted to suppress TNF-α formation. This compound also has disp...
T68153 Tazomeline 131987-54-7 100%
Tazomeline
Tazomeline is a muscarinic M1 receptor agonist with neuroprotective activity.
T13370 YM-46303 171722-81-9 100%
YM-46303
YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia in me...
T5023 Propiverine hydrochloride 54556-98-8 100%
Propiverine hydrochloride
Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).
T1320 Disopyramide 3737-09-5 100%
Disopyramide
Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a me...
T0427 Homatropine Methylbromide 80-49-9 100%
Homatropine Methylbromide
Homatropine Methylbromide is the methyl bromide salt of homatropine, a synthetic tertiary amine alkaloid with antimuscarinic properties.
T12489L Pimethixene maleate 13187-06-9 100%
Pimethixene maleate
Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2...
VU0238441
T8219
VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.
GTS-21 dihydrochloride
T2663
GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh.
Pipecuronium bromide
T12481
Pipecuronium bromide (RGH-1106) is a selective and potent nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker, causing muscle r...
(-)-OPC-51803
T28257L
(-)-OPC-51803 is an antidiuretic hormone V2 receptor agonist used in the treatment of nocturia and urinary incontinence.
Desfesoterodine
T6364
Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.
Procainamide hydrochloride
T0018
Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog ...
Aceclidine
T19870
Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocular pressure...
VU 0238429
T8007
VU 0238429 (SCR-1481B1) is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).
Cevimeline hydrochloride hemihydrate
T2390
Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.
Maprotiline hydrochloride
T0172
Maprotiline hydrochloride (Psymion) is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepre...
CHF5407
T13992
CHF5407(SVT-47060) is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect on bronchospas...
Benztropine mesylate
T1336
Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISE...
BNC210
T8318
BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
Loganin
T2759
Loganin (Loganoside), an iridoid glucoside, has been reported to be an inhibitor of Cox-1 and also noted to suppress TNF-α formation. This compound also has disp...
Tazomeline
T68153
Tazomeline is a muscarinic M1 receptor agonist with neuroprotective activity.
YM-46303
T13370
YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia in me...
Propiverine hydrochloride
T5023
Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).
Disopyramide
T1320
Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a me...
Homatropine Methylbromide
T0427
Homatropine Methylbromide is the methyl bromide salt of homatropine, a synthetic tertiary amine alkaloid with antimuscarinic properties.
Pimethixene maleate
T12489L
Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2...
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TargetMol