T8219 |
VU0238441
|
85511-68-8
|
100%
|
|
VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.
|
T2663 |
GTS-21 dihydrochloride
|
156223-05-1
|
100%
|
|
GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh.
|
T12481 |
Pipecuronium bromide
|
52212-02-9
|
100%
|
|
Pipecuronium bromide (RGH-1106) is a selective and potent nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker, causing muscle r...
|
T28257L |
(-)-OPC-51803
|
192514-57-1
|
100%
|
|
(-)-OPC-51803 is an antidiuretic hormone V2 receptor agonist used in the treatment of nocturia and urinary incontinence.
|
T6364 |
Desfesoterodine
|
207679-81-0
|
100%
|
|
Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.
|
T0018 |
Procainamide hydrochloride
|
614-39-1
|
100%
|
|
Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog ...
|
T19870 |
Aceclidine
|
827-61-2
|
100%
|
|
Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocular pressure...
|
T8007 |
VU 0238429
|
1160247-92-6
|
100%
|
|
VU 0238429 (SCR-1481B1) is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).
|
T2390 |
Cevimeline hydrochloride hemihydrate
|
153504-70-2
|
100%
|
|
Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.
|
T0172 |
Maprotiline hydrochloride
|
10347-81-6
|
100%
|
|
Maprotiline hydrochloride (Psymion) is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepre...
|
T13992 |
CHF5407
|
1004312-94-0
|
100%
|
|
CHF5407(SVT-47060) is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect on bronchospas...
|
T1336 |
Benztropine mesylate
|
132-17-2
|
100%
|
|
Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISE...
|
T8318 |
BNC210
|
13589-06-5
|
100%
|
|
BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
|
T2759 |
Loganin
|
18524-94-2
|
100%
|
|
Loganin (Loganoside), an iridoid glucoside, has been reported to be an inhibitor of Cox-1 and also noted to suppress TNF-α formation. This compound also has disp...
|
T68153 |
Tazomeline
|
131987-54-7
|
100%
|
|
Tazomeline is a muscarinic M1 receptor agonist with neuroprotective activity.
|
T13370 |
YM-46303
|
171722-81-9
|
100%
|
|
YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia in me...
|
T5023 |
Propiverine hydrochloride
|
54556-98-8
|
100%
|
|
Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).
|
T1320 |
Disopyramide
|
3737-09-5
|
100%
|
|
Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a me...
|
T0427 |
Homatropine Methylbromide
|
80-49-9
|
100%
|
|
Homatropine Methylbromide is the methyl bromide salt of homatropine, a synthetic tertiary amine alkaloid with antimuscarinic properties.
|
T12489L |
Pimethixene maleate
|
13187-06-9
|
100%
|
|
Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2...
|