AChE

Acetylcholinesterase, also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.

Cat. No.	Product name	CAS No.	Purity
TN1786	Isomerazin	1088-17-1	98%
TN1786	Isomeranzin has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the p65, NF-κB and ERK pathway.
T7041	Donepezil	120014-06-4	98%
T7041	Donepezil is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE). It can be used for the treatment of mild to moderate ...
T0229	Rivastigmine	123441-03-2	98%
T0229	Rivastigmine is a Cholinesterase Inhibitor, used for therapy of Alzheimer disease.
T5S2360	Corydaline	518-69-4	98%
T5S2360	1. Corydaline, an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and...
T4S1725	Galanthamine	357-70-0	98%
T4S1725	Galanthamine is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.
T1575	Nizatidine	76963-41-2	98%
T1575	Nizatidine is a competitive and reversible histamine H2-receptor antagonist with antacid activity.
T3026	(-)-Huperzine A	102518-79-6	98%
T3026	Huperzine A, an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibit...
TN1091	Dehydronuciferine	7630-74-2	98%
TN1091	Dehydronuciferine is isolated from the leaves of Nelumbo nucifera Gaertn. Dehydronuciferine shows inhibitory of acetylcholinesterase with the IC50 of 25 ug/mL.
T2984	Scopoletin	92-61-5	98%
T2984	Scopoletin is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).
T2191	Tacrine hydrochloride (hydrate)	206658-92-6	98%
T2191	Tacrine hydrochloride hydrate is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxant...
T6478	Donepezil Hydrochloride	120011-70-3	98%
T6478	Donepezil is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM).
T0998	Diazinon	333-41-5	98%
T0998	Diazinon is a thiophosphoric acid ester, functioning as a nonsystemic organophosphate insecticide that effectively targets and controls a variety of pests includ...
T3769	Tenuifolin	20183-47-5	98%
T3769	Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.
T1612	Neostigmine methyl sulfate	51-60-5	98%
T1612	Hodostin is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier, used in the treatment of myasthenia gravis.
TN1124	Neoeriocitrin	13241-32-2	98%
TN1124	Neoeriocitrin is a natural product isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a...
T2846	Isoimperatorin	482-45-1	98%
T2846	Isoimperatorin is an anti-inflammatory agent, exhibits significant inhibitory effects on acetylcholinesterase (AChE).
T3819	Ursolic acid acetate	7372-30-7	98%
T3819	Acetylursolic acid has cytotoxic activity, antimalarial activity, antitumor and anticancer activities. Acetylursolic acid has NO production inhibitory activities...
Fr16605	Lupinine	486-70-4	98%
Fr16605	Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Lora...
TN2298	Vincosamide	23141-27-7	98%
TN2298	Vincosamide is an alkaloid from Psychotria leiocarpa extract, inhibits the acetylcholinesterase (AChE) activity with anti-inflammatory activity. Vincosamide can ...
T2227	Hemicholinium 3	312-45-8	98%
T2227	Hemicholinium-3 is a potent and selective choline uptake blocker.