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Results for "
ym-298198 hydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists2
YM-298198 hydrochloride
YM 298198 hydrochloride
T235481216398-09-2
mGlu1 receptor antagonist
Inquiry
YM 298198 Hydrochloride
T71764748758-45-4
YM 298198 Hydrochloride is a non-competitive antagonist with high affinity and selectivity for mGlu1 receptors (Ki = 19 nM). YM 298198 Hydrochloride is inactive at other mGlu receptor subtypes (mGlu2-7), ionotropic receptors and glutamate transporters (IC50 > 10 μM). It inhibits glutamate-induced IP production more potently than CPCCOEt (IC50 values are 16 nM and 6.3 μM respectively).
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