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veroe6/tmprss2

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
SARS-CoV-2-IN-66
T812051807620-38-7
SARS-CoV-2-IN-66 (1), a derivative of vitamin K, serves as an inhibitor of SARS-CoV-2, with an effective concentration (EC50) of 70.8 μM in VeroE6 TMPRSS2 cells [1].
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8-10 weeks
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SARS-CoV-2-IN-67
T81204
SARS-CoV-2-IN-67 (Compound 16), a vitamin K derivative, exhibits anti-SARS-CoV-2 properties with an effective concentration (EC50) of 64.8 μM in VeroE6 TMPRSS2 cells and inhibits SARS-CoV-2 RdRp activity [1].
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Mefloquine
WR 142490, Ro-215998, Ro215998, Ro 215998, Lariam
T0860L53230-10-7
Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1 minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic lupus erythematosus, and cancer research.
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