vb6

c(avb6)-DOTA TFA is a conjugate formed by the coupling of a selective αvβ6 integrin cyclic peptide and a DPTA chelating agent. The Lu (III) complex of c(avb6)-DOTA TFA exhibits considerable affinity for αvβ6 integrin (IC50=0.8 nM), making it suitable for tumor diagnostics.

Pyridoxine hydrochloride (Vitamin B6) is the 4-methanol form of vitaminB6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.

4-Pyridoxic Acid (4-Pyridoxinsaeure), a catabolite of vitamin B6, is a water-soluble B-group vitamin that can be used as a urinary diagnostic biomarker for determining the nutritional status of these vitamins.

Citatuzumab bogatox (VB6-845) is a recombinant immunotoxin composed of a humanized antibody's Fab fragment targeting EpCAM and a modified bouganin cytotoxin. It selectively binds to EpCAM-positive cell lines, induces apoptosis, and demonstrates efficacy in EpCAM-positive human tumor xenograft models [1] [2] [3].