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unc0638

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
UNC0638
T32571255580-76-7
UNC0638 is an inhibitor of β-protein lysine methyltransferases G9a(IC50<15 nM) and GLP(IC50=19 nM) with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets.
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TargetMol | Citations Cited
UNC0638 hydrate
T2010481255517-77-1
UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 values of 15 nM and 19 nM, respectively. It is effective in inhibiting invasion and migration of TNBC cells in vitro. Additionally, UNC0638 hydrate acts as an inhibitor of EHMT1 2 and induces the expression of fetal hemoglobin (HbF) in cultures of human erythroid progenitor cells. Furthermore, it exhibits antiviral activity against FMDV (foot-and-mouth disease virus) and VSV (vesicular stomatitis virus), demonstrating remarkable potency and selectivity across various epigenetic and non-epigenetic targets.
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10-14 weeks
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UNC0737
UNC-0737,UNC 0737
T34998
UNC0737 is a negative control of UNC0638
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