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tsu 68

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Orantinib
TSU-68, SU6668, NSC 702827
T6184252916-29-3
Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It shows little effect against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2 and does not suppresses EGFR.
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7-Hydroxy-TSU-68
T832411035154-52-9
7-Hydroxy-TSU-68, a derivative and metabolite of TSU-68, originates from the self-induced hydroxylation of TSU-68 in human liver microsomes, indicating its biotransformation pathway [1].
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6-Hydroxy-TSU-68
T832641035154-49-4
6-Hydroxy-TSU-68, a derivative and metabolite of TSU-68, reflects the compound's self-induced hydroxylation in human liver microsomes [1].
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