Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Apoptosis
    (1)
  • IκB/IKK
    (1)
  • STAT
    (1)
  • Others
    (1)
Filter
Search Result
Results for "

tpca-1

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
TPCA-1
GW683965, IKK2 Inhibitor IV, TPCA1
T3049507475-17-4
TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases and enzymes.
  • Inquiry Price
Size
QTY
StA-IFN-1
T38158300839-31-0
StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1 , which specifically inhibits the IKKβ component of the IFN induction pathway. It does not show inhibitory activity in a GFP reporter assay for IFN signaling in which ruxolitinib , which is specific for the IFN signaling component JAK1, is active. StA-IFN-1 reduces the levels of IFN-β, but not ISG MxA, mRNA, suggesting that it is selective for the IFN induction pathway and not the IFN signaling pathway.
  • Inquiry Price
6-8 weeks
Size
QTY