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tofersen

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Tofersen
ISIS-SOD1Rx, ISISSOD1Rx, ISIS333611, ISIS 333611, BIIB-067, BIIB067
T394982088232-70-4
Tofersen (BIIB067) is an antisense oligonucleotide (ASO) that mediates RNase H-dependent degradation of SOD1 (superoxide dismutase 1) mRNA, inhibiting SOD1 protein synthesis for potential use in amyotrophic lateral sclerosis (ALS).
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Tofersen-d27
ISIS-SOD1Rx-d27, ISIS 333611-d27, BIIB067-d27
TMIT-0213
Tofersen-d27 (BIIB067-d27) is the deuterated form of Tofersen. Tofersen (BIIB067) is an antisense oligonucleotide that mediates the RNase H-dependent degradation of superoxide dismutase 1 (SOD1) mRNA, thereby reducing the synthesis of SOD1 protein. Tofersen is utilized in research related to amyotrophic lateral sclerosis (ALS).
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