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Results for "
tie-2 inhibitor 7
" in TargetMol Product Catalog- Inhibitors & Agonists1
tie2 inhibitor 7
T367181020412-97-8
Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 μM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 μM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization.
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