thienamycin

Imipenem monohydrate (Imipenem) is a carbapenem antibiotic isolated from the microorganism Streptomyces cattleya, and is a β lactam antibiotic. Imipenem monohydrate acts on the bacterial cell wall, and is a broadly effective inhibitor of a wide range of Gram-positive and negative bacteria.

(+)-Thienamycin, a powerful broad-spectrum antibacterial and β-lactamase inhibitor, is isolated from Streptomyces cattleya [1].

Epithienamycin E is a member of the class of carbapenems. Epithienamycin E has a role as a bacterial metabolite.

Epithienamycin C is a carbapenem antibiotic with activity against both Gram-positive and Gram-negative bacteria.

Epithienamycin F is a carbapenem antibiotic with activity against both Gram-positive and Gram-negative bacteria.

Epithienamycin D is a carbapenem antibiotic that exhibits activity against both Gram-positive and Gram-negative bacteria.

Epithienamycin B is a natural product isolated from Streptomyces flavoviridis.

Epithienamycin A is a carbapenem antibiotic demonstrating activity against both Gram-positive and Gram-negative bacteria.

Imipenem (MK0787) is a thienomycin derivative that belongs to the class of antibiotics with antibacterial activity and partial inhibition against gram-positive and gram-negative bacteria. Imipenem can be used to study carbapenem non-susceptible infections and Pseudomonas aeruginosa biofilm infections.

MK-789 is an inhibitor of dehydropeptidase I. MK-789 and MK-791 alter the renal excretion of N-formimidoyl thienamycin from glomerular filtration plus tubular secretion to glomerular filtration only, possibly by competitively inhibiting the penetration of