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- Inhibitors & Agonists3
- Isotope Products3
Theophylline-d6
T71329117490-39-8
Theophylline-d6 is intended for use as an internal standard for the quantification of theophylline by GC- or LC-MS. Theophylline is an inhibitor of phosphodiesterase. It is also an adenosine A1 and A2 receptor antagonist. Theophylline induces relaxation of isolated cat bronchial smooth muscle segments precontracted with acetylcholine. It inhibits ovalbumin-induced increases in bronchoalveolar lavage fluid (BALF) eosinophil infiltration in an ovalbumin-sensitized mouse model of allergic asthma. Formulations containing theophylline have been used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
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8-Chlorotheophylline-d6
TMIH-00641346598-95-5
8-Chlorotheophylline-d6 is a deuterated compound of 8-Chlorotheophylline. 8-Chlorotheophylline has a CAS number of 85-18-7.
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Doxofylline-d6
TMID-0118
Doxofylline-d6 is a deuterated compound of Doxofylline. Doxofylline has a CAS number of 69975-86-6. Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies.
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