theophylline-d6

Theophylline-D6 is intended for use as an internal standard for the quantification of theophylline by GC- or LC-MS. Theophylline (T1083) is an inhibitor of phosphodiesterase. It is also an adenosine A1 and A2 receptor antagonist. Theophylline (T1083) induces relaxation of isolated cat bronchial smooth muscle segments precontracted with acetylcholine. It inhibits ovalbumin-induced increases in bronchoalveolar lavage fluid (BALF) eosinophil infiltration in an ovalbumin-sensitized mouse model of allergic asthma. Formulations containing theophylline have been used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

Theophylline-D6 (Standard) is a reference standard of Theophylline-D6 intended for quantitative analysis, quality control, and related biochemical research applications. Theophylline-d6 is used as an internal standard when quantitatively analyzing Theophylline by gas chromatography-mass spectrometry or liquid chromatography-mass spectrometry. Theophylline is a phosphodiesterase inhibitor. It is also an antagonist of adenosine A1 and A2 receptors. Theophylline can cause the relaxation of the bronchial smooth muscle segments that were pre-contracted with acetylcholine in cats.

8-Chlorotheophylline-D6 is a deuterated compound of 8-Chlorotheophylline (PDK0377). 8-Chlorotheophylline (PDK0377) has a CAS number of 85-18-7.

8-Chlorotheophylline-D6 (Standard) is a reference standard of 8-Chlorotheophylline-D6 intended for quantitative analysis, quality control, and related biochemical research applications. 8-Chlorotheophylline-d6 is a deuterated compound of 8-Chlorotheophylline. 8-Chlorotheophylline has a CAS number of 85-18-7.

Doxofylline-D6 is a deuterated compound of Doxofylline. Doxofylline (T0480) has a CAS number of 69975-86-6. Doxofylline (T0480) is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies.

Theophylline-[13C2,D6] (Standard) is a reference standard of Theophylline-[13C2,D6] intended for quantitative analysis, quality control, and related biochemical research applications.