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taltobulin hydrochloride

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Taltobulin hydrochloride
T75240
Taltobulin hydrochloride (HTI-286 hydrochloride), a synthetic analogue of the tripeptide hemiasterlin, effectively bypasses P-glycoprotein-mediated resistance both in vitro and in vivo as a robust antimicrotubule agent. It prevents the polymerization of purified tubulin, destabilizes cellular microtubule structures, and triggers both mitotic arrest and apoptosis [1].
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Taltobulin hydrochloride (228266-40-8 free base)
Taltobulin hydrochloride, SPA-110 hydrochloride, HTI-286 hydrochloride
T13073L
Taltobulin hydrochloride is a synthetic analogue of the tripeptide hemiasterlin, is a potent agent of antimicrotubule that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
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3-6 months
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