t6384

Ammonium glycyrrhizinate (Glycyrram) exhibits diverse pharmacological properties, including anti-inflammatory, antiallergic, antigastriculcer, and antihepatitis activities.

Gefapixant citrate (AF-219 citrate) is an orally available, highly potent P2X3 receptor antagonist with antitussive properties that inhibits hP2X2/3. It can be used to study chronic cough.

Antibacterial agent 115 is an antibacterial and anti-inflammatory agent that is active when taken orally.

BSJ-01-175 is a selective and potent covalent inhibitor of CDK12/13. BSJ-01-175 is significantly selective for cancer cells, exhibits potent inhibition of phosphorylated RNA polymerase II, and significantly downregulates CDK12 target genes.

FTO-IN-5 is a potent, selective inhibitor targeting the fat mass obesity-associated protein (FTO).

PKG1α activator 3, with an EC50(basal/partial) of 13/0.52 μM, inhibits the proliferation of smooth muscle cells and is utilized in cardiovascular disease research.

ATX inhibitor 14, an indole-based carbamate derivative, is a potent inhibitor (IC50: 0.41 nM) of self-adhesive proteins (ATX) and has shown potential for research in fibrosis-related diseases.

Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) is a modified PS product obtained through NADPH oxidase activation and Lyso-PS signal transduction. This compound utilizes macrophage G2A function to enhance the receptor/ligand system, thereby resolving neutrophil inflammation.

TLR8 agonist 4 was effective in inhibiting both wild-type and drug-resistant (lamivudine and entecavir) HBV strains with their IC50 values of 0.15 and 0.10 μM, respectively.

Tubulin polymerization-IN-34 is an inhibitor of [1,2] oxazolylisoindole-based microtubule polymerization and demonstrates high selectivity for marginal zone lymphoma VL51 cell lines.