t-1095

T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).

T-1095A is an active metabolite of T-1095, a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs). Chronic administration of T-1095 (0.1% w w(-1) pellet chow, for 12 weeks) decreased blood glucose and haemoglobin A(1C) levels, and improved

Sparfloxacin (CI-978) is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thus preventing DNA replication and transcription.

DAGLβ-IN-1 is a universal intermediate for designing DAGL tailored activity-based probes, and is an inhibitor of diacylglycerol lipase-β (DAGLβ).

Dabuzalgron (Ro 115-1240), an orally active selective alpha-1A adrenergic receptor agonist, is used to treat urinary incontinence and prevents doxorubicin-induced cardiotoxicity by maintaining mitochondrial function.

Dabigatran ethyl ester hydrochloride is an effective inhibitor of ribosyl dihydronicotinic acid amide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and is a thrombin inhibitor.

Dansyl glutathione is a fluorescent trapping agent and a dansyl-labeled glutathione derivative. it enhances LC-MS/MS sensitivity for reactive metabolite identification in toxicity screening.

Bis(DNS-glutathione) disulfide is a synthetic polypeptide composed of repeating α-L-glutamic acid units. Poly-DNS-glutathione is recognized for its biocompatibility, biodegradability, and non-immunogenic nature, making it highly suitable for advanced drug-delivery system engineering. Bis(DNS-glutathione) disulfide has been extensively employed in the creation of nanomaterials designed to improve drug loading, controlled release, and targeted biodistribution, ultimately supporting the development of safer and more efficient therapeutic delivery platforms.

Dapagliflozin D5 (BMS-512148 D5) is a deuterated form of Dapagliflozin, a competitive SGLT2 inhibitor.

Daphnin is a natural product isolated from Daphne tangutica Maxim that exhibits inhibitory effects on HepG2 and Hep3B cells.