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Results for "
t 2513
" in TargetMol Product Catalog- Inhibitors & Agonists3
T-2513
T40365288247-87-0
T-2513 is a potent and specific inhibitor of topoisomerase I. It acts by forming covalent bonds with the topoisomerase I-DNA complex, thereby enhancing its stability. This interaction disrupts the normal process of DNA replication and RNA synthesis, ultimately resulting in cellular apoptosis.
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T-2513 hydrochloride
T63225187793-52-8
T-2513 hydrochloride, a selective inhibitor of topoisomerase I, covalently binds to the topoisomerase I-DNA complex, stabilizing it and inhibiting DNA replication and RNA synthesis, ultimately leading to cell death.
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Delimotecan
MEN4901,MEN 4901,T-0128,MEN-4901,T 0128
T27141187852-63-7
Delimotecan is a DNA topoisomerase I inhibitor. Delimotecan had a long terminal half-life of 109 h, and relatively high exposures to T-2513 and SN-38 were obtained. The percentage decrease in WBC and absolute neutrophil count significantly correlated with
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