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By Target- Apoptosis
- E1/E2/E3 Enzyme(1)
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Results for "
szl p1-41
" in TargetMol Product Catalog- Inhibitors & Agonists1
SZL P1-41 
T3317222716-34-9
SZL P1-41, a skp2 inhibitor, can prevent assembly of Skp2-Skp1 complexes. It selectively suppresses Skp2 SCF E3 ligase activity but exhibits no effect on the activity of other SCF complexes. It also inhibits Skp2-mediated p27 and Akt ubiquitination in vivo and in vitro. It suppresses the survival of Y cells and Y stem cells by triggering cell senescence and inhibiting glycolysis. It exhibits antitumor effects in multiple animal models and Y cell lines.
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