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By Target- c-Met/HGFR
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Results for "
snu-620
" in TargetMol Product Catalog- Inhibitors & Agonists1
AMG-337
AMG337
T32091173699-31-4
AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337(AMG337) inhibits MET kinase activity (IC50: < 5 nM).
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T703181643590-78-6
AMG-337 monohydrate is a highly selective small molecule MET inhibitor. Aberrant hepatocyte growth factor (HGF)/MET signaling has been implicated in hepatocarcinogenesis, suggesting that MET may serve as an attractive therapeutic target in hepatocellular carcinoma.
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