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Results for "
smurf1inhibitor1
" in TargetMol Product Catalog- Inhibitors & Agonists2
AC430
T708701361415-84-0
AC430 is a potent and specific small molecule inhibitor of janus kinase 2 (JAK2), which has been implicated as a target for therapy in both oncology and autoimmune disease. AC430 is currently being developed by Ambit. In preclinical studies, AC430 has exhibited potency against JAK2 and V617F mutated JAK2 in cell-based models that is at least equivalent to, and in most cases superior to, competing JAK2 inhibitors. In preclinical oncology and autoimmune models, AC430 is well tolerated and has significant efficacy at oral doses as low as 10 mg kg day.
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Smurf1 inhibitor 1
T70872136068-42-3
Smurf1 inhibitor 1 is a inhibitor that promotes bone formation.
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