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By Target- S1P Receptor
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Results for "
slr 080811.
" in TargetMol Product Catalog.- Inhibitors & Agonists3
SLR080811
T2151331449765-65-4
SLR080811 is a guanidine-based selective inhibitor of sphingosine kinase 2 (SphK2) with a Ki value of 1.3 μM, demonstrating approximately 10-fold selectivity over SphK1 (Ki = 12 μM). In vitro, it reduces sphingosine-1-phosphate (S1P) levels, but in mice, it can induce SphK1-dependent S1P level increases. SLR080811 is applicable in cancer and fibrosis research.
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Iso-SLR 080811
Iso-SLR080811, 1-Pyrrolidinecarboximidamide, 2-[3-(4-octylphenyl)-1,2,4-oxadiazol-5-yl]-, hydrochloride (1:1), (2R)-, (2R)-2-[3-(4-octylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carboximidamide hydrochloride
T706141449768-36-8
Iso-SLR 080811 is an isomer of SLR 080811, suitable for relevant research in the life sciences. SLR080811 is a selective SphK2 inhibitor (Ki=1.3 μM) that elevates blood S1P levels in wild-type mice, reduces S1P levels in sphk1 knockout mice, and leaves S1P levels unchanged in SphK2 knockout mice.
- $293
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