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sirt2-in-11

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
sirt2-in-11
T730001005095-06-6
SIRT2-IN-11 (AEM1) is a selective inhibitor of SIRT2 with an inhibitory concentration (IC50) of 18.5 μM. It induces apoptosis in a p53-dependent manner, activates the expression of CDKN1A, PUMA, and NOXA, and enhances the acetylation of p53. This compound is utilized in the study of p53-associated cancers.
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6-8 weeks
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