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By Target- Histone Methyltransferase
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Results for "
sgc-0946
" in TargetMol Product Catalog- Inhibitors & Agonists2
SGC0946
Cited
T30821561178-17-3
SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.
- $37
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CitedSGC0946 TFA
T211545
SGC0946 TFA is a selective inhibitor of DOT1L with an IC50 value of 0.3 nM. It induces G1 phase arrest in cancer cells by inhibiting DOT1L and reduces cellular self-renewal and metastatic potential while promoting cell differentiation. SGC0946 TFA is applicable in research for tumors such as leukemia and breast cancer and serves as a probe for studying the cellular mechanisms of DOT1L in both normal and diseased cells.
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