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sb612111

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SB-612111
T36376371980-98-2
SB-612111 is a novel and potent human opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki = 0.33 nM). It exhibits selectivity for μ-, κ-, and δ-receptors with Ki values of 57.6 nM, 160.5 nM, and 2109 nM, respectively. SB-612111 effectively antagonizes the pronociceptive action of Nociceptin in an acute pain model[1].
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10-14 weeks
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rel-SB-612111 hydrochloride
SB 612111 hydrochloride
T23324371980-94-8
NOP receptor antagonist
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10-14 weeks
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