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(8)
By Target- CDK
- VEGFR(2)
- Cell Cycle Arrest(1)
- Cytochromes P450(1)
- Drug Metabolite(1)
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Results for "
ribociclib
" in TargetMol Product Catalog- Inhibitors & Agonists11
- PROTAC Products1
- Isotope Products4
- Cell Research1
Ribociclib
Cited
LEE011
T61991211441-98-3
Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor (IC50:10/39 nM).
- $36
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QTY
CitedRibociclib succinate hydrate
LEE011 succinate hydrate
T157311374639-79-8
Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent against the cyclin B/CDK1 complex.
- Inquiry Price
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Ribociclib succinate
LEE011 succinate
T157321374639-75-4
Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and exhibits over 1,000-fold reduced potency against the cyclin B/CDK1 complex.
- $30
Size
QTY
Ribociclib hydrochloride
LEE011 hydrochloride, LEE 011 hydrochloride
T157301211443-80-9
Ribociclib hydrochloride (LEE011 HCl) is a selective, orally active cyclin-dependent kinase CDK4/6 inhibitor (IC50=10/39 nM) that blocks cell cycle progression and inhibits tumor cell proliferation.
- $30
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LEQ803
N-Desmethyl Ribociclib
T2064491211441-59-6
LEQ803 (N-DesmethylRibociclib) is a metabolite of the CDK4/6 inhibitor Ribociclib, produced through metabolism by CYP3A4. This compound holds potential applications in the field of oncology.
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Ribociclib-d6
LEE011-d6, LEE 011-d6
TMID-00031328934-40-2
Ribociclib-d6 (LEE011-d6) is a deuterated compound of Ribociclib (LEE011) for isotope tracing.Ribociclib is an orally available CDK4/6 inhibitor with antitumor activity.
- $457
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Ribociclib-d6 hydrochloride
TMID-0398
Ribociclib-d6 (hydrochloride) is a deuterated form of Ribociclib, which is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and has over 1000-fold lower activity against the cyclin B/CDK1 complex.
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Ribociclib-d8
TMID-11082167898-24-8
Ribociclib-d8 is the deuterated form of Ribociclib, also known as LEE011, which acts as a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM. Its activity against the cyclin B/CDK1 complex is over 1000 times weaker.
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Ribociclib-d6 HCl
TMIH-0493
Ribociclib-d6 HCl is a deuterated compound of Ribociclib HCl. Ribociclib HCl has a CAS number of 1211443-80-9.
- $457
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LO-3-63
T211507
LO-3-63 is a Ribociclib analogue featuring a truncated fumaramide group and acts as a CDK4/6 degrader with PROTAC properties. It degrades CDK4/6 in cells via a CUL4DCAF16-dependent pathway.
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DOTA-RBB-Ga
TSH-00533
DOTA-RBB-Ga is a conjugate of the chelating agent DOTA, the CDK4/6 inhibitor Ribociclib, and gallium Ga. When labeled with the radioactive isotope gallium-68 ([68Ga]), DOTA-RBB-Ga can serve as a PET radiotracer for CDK4/6-positive tumors.
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