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(3)
By Target- Autophagy
- HDAC(3)
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By Target By ResearchField- Cancer(2)
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Results for "
px-105684
" in TargetMol Product Catalog.- Inhibitors & Agonists3
- Isotope Products1
Rac-Belinostat
Cited
PXD101, PX-105684, NSC726630
T1852414864-00-9
Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
- $37
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QTY
CitedBelinostat Cited
PXD-101, PXD101, PX105684
T8517866323-14-0
Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.
- $40
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QTY
CitedBelinostat-d5
PXD101-d5, PX105684-d5
TMIT-03702130852-65-0
Belinostat-d5 (PXD101-d5) is the deuterium-labeled form of Belinostat. Belinostat (PXD101; PX105684) acts as a potent HDAC inhibitor, with an IC50 of 27 nM in HeLa cell extracts.
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