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(2)
By Target- Bcl-2 Family
- PROTACs(2)
- Akt(1)
- Apoptosis(1)
- Cannabinoid Receptor(1)
- ERK(1)
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By Target By ResearchField- Cancer(1)
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Results for "
protac bcl2 degrader 1
" in TargetMol Product Catalog- Inhibitors & Agonists2
- PROTAC Products2
PROTAC Bcl2 degrader-1
T104852378801-85-3
PROTAC Bcl2 degrader-1 is a PROTAC, which potently and selectively induces the degradation of Mcl-1 (IC50: 11.81 μM) and Bcl-2 (IC50: 4.94 μM; DC50: 3.0 μM).
- $1,200
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PROTAC CB1R Degrader-1
T215202
PROTACCB1R Degrader-1 is a potent and selective CB1R PROTAC degrader that employs the ubiquitin-proteasome system (UPS) to facilitate CB1R degradation, showing a DC50 of 3.37 μM in MCF-7 cells while exhibiting no effect on CB2R. It reduces CB1R-associated downstream signaling pathways (p-AKT, p-ERK, BCL2, and MCM5), thus inhibiting breast cancer cell proliferation and inducing apoptosis. PROTACCB1R Degrader-1 is applicable for breast cancer-related research.
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