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By Target- Apoptosis
- Chk(1)
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Results for "
prexasertib lactate
" in TargetMol Product Catalog- Inhibitors & Agonists2
Prexasertib lactate
LY2606368 lactate
T883642781996-46-9
Prexasertib lactate is the lactate salt form of Prexasertib and functions as a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of less than 1 nM. It also inhibits CHK2 (IC50 = 8 nM) and RSK1 (IC50 = 9 nM). This compound induces double-strand DNA breaks and replication stress, leading to apoptosis (cell death), and exhibits antitumor activity.
- $1,670
Size
QTY
Prexasertib lactate hydrate
Prexasertib monolactate monohydrate salt, Prexasertib monolactate monohydrate, LY-2606368 lactate hydrate, LY2606368 lactate hydrate, LY 2606368 lactate hydrate
T4310L2100300-72-7
Prexasertib is an effective and selective Chk1/Chk2 inhibitor. Prexasertib causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms.
- $1,520
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QTY
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