phthalide

1. 3-Butylidenephthalide (Butylidene phthalide) has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM.

Phthalide-3-acetic acid ,with CAS No. 4743-58-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Phthalide-3-acetic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

6-Aminophthalide ,with CAS No. 57319-65-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-Aminophthalide provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Benzalphthalide (NSC-2824) is a chemical compound with anti-HIV activity.

Butylphthalide (3-Butylphthalide) is an anti-cerebral-ischemia drug; first isolated from the seeds of Apium graveolens Linn.

6-NITROPHTHALIDE, with CAS No. 610-93-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-NITROPHTHALIDE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4,5,6,7-Tetrachlorophthalide is a fungicide used for the control of rice blast. It has a role as a melanin synthesis inhibitor and an antifungal agrochemical.

(3S)-Butylphthalide, a tetrachloro phthalide, can be extracted from carnation. It exhibits antiplatelet and neuroprotective effects.

Butylphthalide-d7 is a deuterated compound of Butylphthalide. Butylphthalide has a CAS number of 6066-49-5. Butylphthalide is an anti-cerebral-ischemia drug; first isolated from the seeds of Apium graveolens Linn.

3-Butylphthalide-d9 is a deuterated compound of 3-Butylphthalide. 3-Butylphthalide has a CAS number of 6066-49-5. Butylphthalide is an anti-cerebral-ischemia drug; first isolated from the seeds of Apium graveolens Linn.

(Z)-Butylidenephthalide ((Z)-3-Butylidenephthalide) has antitumor and hypoglycemic effects, and can effectively inhibit the tumor growth of glioma and inhibit R-glucosidase activity.

5,7-Dihydroxyphthalide is a natural product for research related to life sciences. The catalog number is TN5688 and the CAS number is 27979-58-4.

3-butylidene-4,5-dihydroxyphthalide is a natural product that can be used in related research in the field of life sciences. Its product number is TN8841.

5-Bromophthalide is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

5,7-Dimethoxy-2-benzofuran-1(3H)-one is a phthalide isolated from Italian waxflower with good anti-inflammatory activity.

Mycophenolic Acid Impurity (5,7-dihydroxy-4-methylphthalide) is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of triple therapy including a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also useful in research for the selection of animal cells that express the E. coli gene coding for XGPRT (xanthine guanine phosphoribosyltransferase).

Emeguisin A is a depsidone fungal metabolite originally isolated fromE. unguis.1It is active against the bacteriaS. aureusand methicillin-resistantS. aureus(MRSA; MIC = 0.5 μg/ml for both), the fungusC. neoformans(MIC = 0.5 μg/ml), and the protozoanP. falciparum(IC50= 2.2 μM).2 1.Kawahara, N., Nozawa, K., Nakajima, S., et al.Isolation and structures of novel fungal depsidones, emeguisins A, B, and C, from Emericella unguisJ. Chem. Soc., Perkin Trans. 12611-2614(1988) 2.Klaiklay, S., Rukachaisirikul, V., Aungphao, W., et al.Depsidone and phthalide derivatives from the soil-derived fungus Aspergillus unguis PSU-RSPG199Tetrahedron Lett.57(39)4348-4351(2016)

Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery.

Asperglaucin A, an atypical phthalide-like derivative, exhibits potent antibacterial activities, demonstrating effectiveness against the plant pathogens Pseudomonas syringae pv actinidae (Psa) and Bacillus cereus, with a minimum inhibitory concentration (MIC) of 6.25 μM [1].

Senkyunolide J, a phthalide isolated from the rhizome of Ligusticum Chuanxiong [1], exhibits medicinal properties.