photoactivated

Optovin is a TRPA1 activator, which is reversibly photoactivated.

Methoxsalen (NCI-C55903) is a Photoactivated Radical Generator and Psoralen. The mechanism of action of methoxsalen is as a Photoabsorption. The physiologic effect of methoxsalen is by means of Photosensitizing Activity.

ZnPc-amide-PEG3-C2-NH2 is a photosensitizer-linker conjugate composed of ZnPcPs and a linker. It can be utilized in the synthesis of the photoactivated BRD4 degrader pZnPc-O3-JQ1.

[Ru(dpp)(bpy)(mtmp)](PF6)2 (Compound 5) is a ruthenium-based coordination complex with three chelating ligands. It exhibits photoactivated anticancer properties. Under green light irradiation, [Ru(dpp)(bpy)(mtmp)](PF6)2 selectively cleaves, releasing a phototoxic ruthenium-based product that binds to nuclear DNA, inducing DNA damage and apoptosis in cancer cells. This compound is applicable for phototherapy research on cancers such as conjunctival melanoma.

RuOPt is a photoactivated Ru(II)-Pt(IV) complex characterized by low dark toxicity. Upon illumination, RuOPt can induce apoptosis, generate reactive oxygen species (ROS), and inhibit the growth of tumor spheroids, thereby demonstrating significant phototoxicity.

Ovothiol A TFA (108418-13-9 Free base) is a hexaalkyl multifunctional biomolecule that counteracts oxidative stress. When photoactivated to its oxidized state, it inactivates the CF1 (coupling factor 1) ATPase of Dunaliella salina.

Methoxsalen (Standard) is the standard substance of Methoxsalen, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Methoxsalen (NCI-C55903) is a Photoactivated Radical Generator and Psoralen. The mechanism of action of methoxsalen is as a Photoabsorption. The physiologic effect of methoxsalen is by means of Photosensitizing Activity.

4-Azide-TFP-amide-SS-propionic acid contains an aryl azide, a cleavable disulfide bond, and a carboxylic acid. The aryl azide can be photoactivated by ultraviolet light (250 to 350 nm) to bind with biomolecules. Fluorine helps stabilize radical intermediates. The carboxylic acid can react with amines in the presence of an activating agent to form an amide bond. The disulfide bond can be cleaved by a reducing agent.

4-Azide-TFP-amide-SS-Sulfo-NHS comprises an aryl azide, a cleavable disulfide bond, and an NHS ester. The aryl azide can be photoactivated by ultraviolet light (250 to 350 nm) to bind with biomolecules, while fluorine aids in stabilizing radical intermediates. The NHS ester reacts with amines, and the disulfide bond is cleavable by reducing agents.

4-Azide-TFP-amide-PEG4-acid contains an aryl azide and a carboxylic acid, with a PEG spacer to enhance solubility and reduce steric hindrance during the conjugation process. The aryl azide can be photoactivated by UV light (250 to 350 nm) to bond with biomolecules. Fluorine stabilizes radical intermediates. The carboxylic acid can react with amines in the presence of a coupling agent to form an amide bond.

18:0-azo PC is an analog of phosphatidylcholine (PC). Upon exposure to light, it can be photoactivated or deactivated, causing the azobenzene segment within the molecule to undergo cis/trans isomerization, thereby initiating or terminating cell signaling pathways.