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Results for "
pf 06672131
" in TargetMol Product Catalog- Inhibitors & Agonists2
PF-06672131
T703691621002-27-4
PF-06672131 is a selective EGFR kinase inhibitor.
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SF0166
T703681621332-91-9
SF0166 is a potent, selective antagonist of α v β 3, demonstrating IC 50 values of 0.6 nM for α v β 3, 8 nM for α v β 6, and 13 nM for α v β 8. It effectively inhibits cellular adhesion to vitronectin in human, rat, rabbit, and dog cell lines, with IC 50 values ranging from 7.6 pM to 76 nM. Additionally, SF0166 significantly reduces neovascularization in the oxygen-induced retinopathy mouse model.
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