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pentetrazol

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  • Inhibitors & Agonists
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Pentetrazol
PTZ, Pentylenetetrazole, Pentylenetetrazol, pentamethylenetetrazol, Metrazole, Cardiazol
T141354-95-5
Pentylenetetrazol is a GABA(A) receptor antagonist, that displays activity as a central nervous system and respiratory stimulant.
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GABAA receptor modulator-10
T213145
GABAA receptor modulator-10 is an orally active and potent positive allosteric modulator (PAM) of the α1β2γ2GABAA receptor, exhibiting good blood-brain barrier permeability. It enhances the function of the α1β2γ2 GABAA receptor and increases GABA-induced currents. In mouse models of epilepsy induced by Pentetrazol (PTZ) and Kainic Acid (KA), GABAA receptor modulator-10 demonstrates strong antiepileptic efficacy. This compound shows potential for epilepsy research.
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