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By Target- Apoptosis
- COX(1)
- NEDD8(1)
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- GPR
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- GTPase
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- Histamine Receptor
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- LPA Receptor
- LPL Receptor
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Results for "
pelubiprofen
" in TargetMol Product Catalog- Inhibitors & Agonists2
Pelubiprofen
T1646469956-77-0
Pelubiprofen is an orally active, non-steroidal anti-inflammatory agent, a selective cyclooxygenase-2 (COX-2) inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity. Pelubiprofen inhibits LPS-induced phosphorylation of IKK-β and transforming growth factor-β activated kinase-1 (TAK1).
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Pevonedistat hydrochloride
MLN-4924 hydrochloride, MLN4924 hydrochloride, MLN 4924 hydrochloride
T161171160295-21-5
Pevonedistat hydrochloride (MLN4924 hydrochloride) is a selective and potent NEDD8 activating enzyme inhibitor (IC50: 4.7 nM) that induces apoptosis and cell cycle inhibition in cancer cells, and is used in the study of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Pelubiprofen has been used in the study of AML and MDS.)
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