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p-smad3

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
  • Recombinant Protein
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    TargetMol | Recombinant_Protein
TGFβ-IN-2
T615862387678-02-4
TGFβ-IN-2 (Compound 9d) effectively inhibits TGF-β-induced accumulation of total collagen in NRK-49F cells, with an IC50 value of 4.31 μM. It also suppresses the TGF-β-induced in vitro expression of COL1A1, α-SMA, and p-Smad3. Additionally, TGFβ-IN-2 shows promise as a potential anti-fibrosis compound for in vivo applications through oral administration [1].
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6-8 weeks
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NCGC00378430
T9205920650-00-6
NCGC00378430 is a potent SIX1 EYA2 interaction inhibitor that disrupts the [SIX1 EYA2] complex, EMT, and metastasis.
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