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By Target- Apoptosis
- FGFR(1)
- PDGFR(1)
- VEGFR(1)
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Results for "
orantinib
" in TargetMol Product Catalog- Inhibitors & Agonists2
orantinib
TSU-68, SU6668, NSC 702827
T6184252916-29-3
Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It shows little effect against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2 and does not suppresses EGFR.
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(z)-orantinib
T9684210644-62-5
(Z)-Orantinib ((Z)-SU6668) is a potent, selective, orally active, and ATP-competitive inhibitor of Flk-1 KDR, PDGFRβ, and FGFR1, with IC50 values of 2.1, 0.008, and 1.2 μM, respectively. (Z)-Orantinib is an effective antiangiogenic and antitumor agent that induces established tumor regression [1] [2].
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