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Results for "
nsc-52361
" in TargetMol Product Catalog- Inhibitors & Agonists1
VPC-13163
VPC13163, VPC 13163, NSC52361, NSC 52361, 2,3-dihydro-2,3'-Bi-1H-indole
T291106637-10-1In house
VPC-13163 (NSC-52361) has strong anti-proliferative activity against LNCaP and Enzalutamide-resistant prostate cancer cell lines (MR49F) whereas it did not affect the growth of AR independent PC3 cell line. It also inhibits Prostate Specific Antigen (PSA) in both LNCaP and MR49F and reduces expression of AR target genes, PSA and TMPRSS2. These findings suggest that VPC-13566 exhibits AR BF3 specific mechanism of action.
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