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nox3

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
  • Recombinant Protein
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    TargetMol | Recombinant_Protein
ML-090
Fluoflavine
T22990531-46-4In house
ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).
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6-8 weeks
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APX-115 free base
Ewha-18278 free base
T103531270084-92-8
APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with inhibition constants (Kis) of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4, respectively, and it effectively prevents kidney injury.
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