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By Target- ALK
- Autophagy(1)
- ROS(1)
- ROS Kinase(1)
- Trk receptor(1)
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Results for "
nms-e 628
" in TargetMol Product Catalog- Inhibitors & Agonists1
Entrectinib
Cited
RXDX-101, NMS-E628
T36781108743-60-7
Entrectinib (RXDX-101) is a Trk, ROS1, and ALK inhibitor that inhibits TrkA, TrkB, TrkC, ROS1, and ALK (IC50=1 3 5 12 7 nM) with oral activity and blood-brain-barrier penetration. Entrectinib exhibits both antitumor and CNS activity.
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