nivalenol

Nivalenol is a fungal metabolite produced by Fusarium graminearum. Nivalenol induces cell death through caspase and intrinsic apoptotic pathways thus affecting the immune system and causing emesis, growth retardation, and reproductive disorders.

13C15-Nivalenol is intended for use as an internal standard for the quantification of nivalenol by GC- or LC-MS. Nivalenol (T13797) is a trichothecene mycotoxin that has been found inFusarium.1It is lethal to mice (LD50= 6.9 mg/kg).2Nivalenol (5, 10, and 15 mg/kg) also induces thymic, splenic, and Peyer's patch cell apoptosis in mice.3

3-Acetyldeoxy Nivalenol-13C17 is intended for use as an internal standard for the quantification of 3-Acetyldeoxy Nivalenol (T13493) by GC- or LC-MS. 3-Acetyldeoxy Nivalenol is a mycotoxin that has been found in F. graminearum.

4-deoxy Nivalenol-13C15 is intended for use as an internal standard for the quantification of 4-deoxy nivalenol by GC- or LC-MS. 4-deoxy Nivalenol (T15097) is a trichothecene mycotoxin that has been found inFusarium.1It binds to eukaryotic ribosomes and inhibits protein synthesis in mice when administered at doses ranging from 5 to 25 mg/kg. 4-deoxy Nivalenol (T15097) (0.1 and 0.2 mg/kg) induces emesis in pigs and decreases feed consumption in pigs when administered at a dose of 40 ppb in the diet.2It induces lethality in mice (LD50= 46-78 mg/kg).34-deoxy Nivalenol has been found inF. graminearum-infected cereal grains such as wheat, barley, and corn.

Deoxynivalenol (Vomitoxin) is an orally active mycotoxin belonging to the trichothecenes family, which traverses the intestinal mucosa via the paracellular pathway without being affected by P-gp/MRP, used for research on gastrointestinal inflammation such as diarrhea and vomiting.

15-Acetyl-deoxynivalenol, a highly toxic trichothecene found in cereals, exhibits toxicity to HepG2 cells.

3-Acetyldeoxynivalenol is a mycotoxin discovered in F. graminearum that can penetrate the blood-brain barrier and induce necrosis in mouse duodenal and spleen cells.

Deepoxy-deoxynivalenol is Metabolite of deoxynivalenol. Deepoxydeoxynivalenol is a macrocyclic polyol compound for proteomics research. Environmental contaminants; Food contaminants.

Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside) is a plant metabolite of the Fusarium mycotoxin Deoxynivalenol, exhibiting lower toxicity than Deoxynivalenol in vitro and in vivo [1][2].