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n1,n11-diethylnorspermine

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  • Inhibitors & Agonists
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N1,N11-Diethylnorspermine
T60348121749-39-1
N1,N11-Diethylnorspermine (DENSPM), a spermine analog, serves as a potent anticancer agent by activating polyamine catabolism, which in turn triggers cytochrome c release from mitochondria and activates caspase 3. This process ultimately leads to the death of glioblastoma multiforme (GBM) cells by inducing spermidine spermine N1-acetyltransferase (SSAT) activity along with the production of H2O2 [1] [2] [3].
  • $1,520
6-8 weeks
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Diethylnorspermine HCl
T9640156886-85-0In house
Diethylnorspermine HCl (N1,N11-Diethylnorspermine tetrahydrochloride) potently induces SSAT (spermidine spermine N1-acetyltransferase) mRNA and effectively stabilizes SSAT enzyme activity.
  • $45
In Stock
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