n phenyl 2 pyrimidinamine

N-Phenyl-2-pyrimidinamine, with CAS No. 57356-49-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. N-Phenyl-2-pyrimidinamine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Pyridinamine, 4-[3-fluoro-5-(4-morpholinyl)phenyl] (Compound 9l) is an ATP-competitive JNK (c-Jun N-terminal kinase) inhibitor with IC₅₀ values of 0.099 μM and 0.148 μM for JNK1 and JNK3 respectively, exhibiting the advantage of blood-brain barrier penetration. 2-Pyridinamine, 4-[3-fluoro-5-(4-morpholinyl)phenyl] inhibits c-Jun phosphorylation and reactive oxygen species (ROS) generation, making it suitable for neurodegenerative disease research.