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(2)
By Target- Autophagy
- Antioxidant(1)
- Fatty Acid Synthase(1)
- Mitochondrial Metabolism(1)
- Others(2)
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Results for "
mitochondrial long-chain 3-ketoacyl thiolase
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Recombinant Protein1
Trimetazidine dihydrochloride
Cited
Yoshimilon, Vastarel F, Kyurinett
T098813171-25-0
Trimetazidine dihydrochloride (Vastarel F) can improve myocardial glucose utilization by inhibiting fatty acid metabolism. Trimetazidine is the first cytoprotective anti-ischemic agent, also used as a vasodilator in ischemic heart disease or angina.
- $34
Size
QTY
CitedTrimetazidine
T224445011-34-7
Trimetazidine is a non-haemodynamic antianginal agent that selectively inhibits the mitochondrial enzyme 3-ketoacyl coenzyme A thiolase (LC 3-KAT), thereby preventing β-oxidation of free fatty acids, with an IC50 value of 75 nM. Trimetazidine prevents ischaemia-reperfusion injury by altering cardiac metabolism, exhibiting antioxidant and anti-ischaemic effects.
- $32
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QTY
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