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By Target- TRP/TRPV Channel
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Results for "
m-084 hydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists3
M 084 hydrochloride
T37823
TRPC4/5 channel blocker (IC50 values are 3.7-10.3 and 8.2 μM, respectively). Also weakly blocks TRPC3 channels. Exhibits rapid antidepressant and anxiolytic effects in vivo. Zhu et al (2015) Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels. Br.J.Pharmacol. 172 3495 PMID:25816897 |Yang et al (2015) Acute treatment with a novel TRPC4/C5 channel inhibitor produces antidepressant and anxiolytic-like effects in mice. PLoS One 10 e0136255 PMID:26317356
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M084 hydrochloride
T849001992047-63-8
M084 hydrochloride, a TRPC4/5 channel blocker, exhibits IC50 values of 10.3 μM and 8.2 μM, respectively. This compound is noted for its antidepressant and anxiolytic effects [1] [2].
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M084
1H-Benzimidazol-2-amine,N-butyl-(9CI), N-Butyl-1H-benzimidazol-2-amine
T860751314-51-3
M084 (N-Butyl-1H-benzimidazol-2-amine) is a blocker of TRPC4 5 channel, with antidepressant and anxiolytic effects.
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