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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8926 | Salcaprozate sodium | SNAC | Others |
Salcaprozate sodium (SNAC), an oral absorption promoter, serves as a potent delivery agent for oral heparin and insulin by enhancing passive transcellular permeation through small intestinal epithelia. This is achieved t... | |||
T33604 | Z-Glycine | Carbobenzoxyglycine,N-Carbobenzoxyglycine | Others |
Z-Glycine (Carbobenzoxyglycine) is a drug-lipid conjugates designed to promote brain penetration based on its lipophilicity and resemblance to lipids in biological membranes[1]. | |||
T9527 | Span-85 | Sorbitan trioleate | Others |
Span-85 (Sorbitan trioleate) is a synthetic non-ionic emulsifier, which is prepared by partial esterification of sorbitol or sorbitan with food grade palmitic acid. It has low viscosity and the smallest HLB value, so it ... | |||
T33606 | NBI-30545 | ||
NBI-30545 is a potent corticotropin-releasing factor-1 antagonist with sufficient lipophilicity and water solubility for the treatment of stress disorders. | |||
T70316 | AZD6642 | ||
AZD6642 is a potential and selective 5-Lipoxygenase activating Protein (FLAP) inhibitor. AZD6642 shows high specific potency and low lipophilicity resulting in a selective and metabolically stable profile. Based on initi... | |||
T83130 | AMCPy | ||
AMCPy, a potent electron paramagnetic resonance (EPR) brain imaging agent, boasts excellent lipophilicity, facilitating its penetration through the blood-brain barrier (BBB) [1]. | |||
T83084 | Anticancer agent 162 | ||
Anticancer agent 162 (compound 1d) serves as a potent theranostic agent, selectively inducing oncosis in Hela cells with pronounced lipophilicity and cytotoxicity [1]. | |||
T82727 | Chromoionophore XIII | SNARF-DE | |
Chromoionophore XIII (SNARF-DE), functioning as a pH sensor, is excitable with red light. Its unique properties impart lipophilicity and prevent the lactonization of the dye in apolar environments, ensuring the molecule'... | |||
T63517 | BuChE-IN-4 | ||
BuChE-IN-4 is a potent inhibitor of BuChE (IC50: 7.7 nM) and exhibits mild antioxidant capacity, non-toxicity, lipophilicity and neuroprotective effects. | |||
T72318 | Trandolaprilate hydrate | Trandolaprilat hydrate ; RU 44403 hydrate,RU 44403 hydrate,Trandolaprilat hydrate | |
Trandolaprilate hydrate, the main bioactive metabolite of Trandolapril and a potent angiotensin-converting enzyme (ACE) inhibitor, exhibits high lipophilicity and partially inhibits angiotensin-I-mediated c-fos induction... | |||
T81609 | Omega-3 Arachidonic acid ethyl ester | (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester,ω-3 Arachidonic acid ethyl ester | |
Omega-3 Arachidonic Acid ethyl ester, a rare polyunsaturated fatty acid with limited presence in dietary sources, is crucial for infant growth and development and offers protection against heart disease, blood clots, hig... | |||
T37831 | CAY10641 | ||
Cytosolic phospholipase A2α (cPLA2α) specifically catalyzes the hydrolysis of arachidonic acid from thesn-2-ester position of membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins a... |