linezolid-d-3

Linezolid D3, a deuterium-labeled version of Linezolid, is a synthetic antibiotic designed to halt the initiation of bacterial protein synthesis.

Linezolid-D3 (Standard) is a reference standard of Linezolid-D3 intended for quantitative analysis, quality control, and related biochemical research applications. Linezolid D3 is the deuterium-labeled isotope of Linezolid. It is an artificially synthesized antibiotic designed to inhibit the initiation process of bacterial protein synthesis.

CAY10742 is an orally bioavailable oxadiazole antibiotic.1It is active against the Gram-positive bacteriaS. aureus,S. epidermidis,S. haemolyticus,B. cereus,B. licheniformis,E. faecalis, andE. faecium(MICs = 1-4 μg/ml), including laboratory strains and clinical isolates with varying degrees of resistance to methicillin, vancomycin, linezolid, and other antibiotics. CAY10742 (40 mg/kg) reduces the number of bacteria in mouse neutropenic thigh models of linezolid-sensitive or -resistant methicillin-resistantS. aureus(MRSA) infection. 1.Boudreau, M.A., Ding, D., Meisel, J.E., et al.Structure-activity relationship for the oxadiazole class of antibacterialsMed. Chem. Lett.11(3)322-326(2019)